Discovery and pre-clinical evaluation of antibodies to the NKG2A inhibitory receptor
D.-S. Baek, Y.-J. Kim, W. Li, B. J. Macatangay, J. C. Cyktor, M. G. Hines, J. W. Mellors, D. S. Dimitrov
The paper discovers and evaluates two fully human antibodies that inhibit NKG2A, an inhibitory receptor on NK and CD8+ T cells, enhancing anti-cancer immune responses.
bioRxiv · May 18, 2022 · PreprintImmunology