Neprilysin 1 in the Mushroom Body controls Feeding behavior by regulating SIFamide levels in Drosophila melanogaster
El‐Sayed Baz, Daan Moons, Maria Pons-Vizcarra, Veerle Vulsteke, Sofie De Groef, Isabelle Rahioui, Jiajun Zhang, Pedro Da Silva, Thomas Dieter Riemensperger, Federica Calevro, Patrick Callaerts
This study identifies Neprilysin 1 in the mushroom bodies as a regulator of SIFamide levels, which control feeding behavior in Drosophila melanogaster by shaping SIFamidergic signaling.
bioRxiv · Oct 12, 2026 · PreprintAnimal Behavior & Cognition