Novel transplantable mouse cell line model recapitulates invasive lobular breast carcinoma (ILC) phenotype and immune microenvironment.
Sayali Onkar, Daisong Liu, Darcie D. Seachrist, Jian Zou, Christopher Merkel, Insa Thale, Alexander Chih-Chieh Chang, Linda R. Klei, Jian Chen, Kristen L. Weber-Bonk, Kai Ding, Laura Savariau, Megan E. Yates, Jagmohan Hooda, Laura P. Stabile, , Steffi Oesterreich
The paper develops a novel mouse cell line model of invasive lobular breast carcinoma that recapitulates human tumor phenotype and immune microenvironment, offering a preclinical platform for therapy evaluation.
bioRxiv · Jul 31, 2026 · PreprintCancer Biology