Author

Dan L Nicolae

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

GTEx Consortium· 2 shared Hae Kyung Im· 2 shared Heather E Wheeler· 2 shared Keston Aquino-Michaels· 2 shared Nancy J Cox· 2 shared Anne E Eyler· 1 shared Carole OberiD· 1 shared Catherine IgartuaiD· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

GTEx Consortium

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3 papers

Recent·Most cited

Survey of the Heritability and Sparsity of Gene Expression Traits Across Human Tissues

Heather E Wheeler, Kaanan P Shah, Jonathon Brenner, Tzintzuni Garcia, Keston Aquino-Michaels, GTEx Consortium, Nancy J Cox, Dan L Nicolae, Hae Kyung Im

The paper surveys heritability and sparsity of gene expression traits across human tissues, finding local heritability is sparse and current sample sizes limit distal heritability analysis.

bioRxiv · Sep 8, 2016Genomics

Host genetic variation in mucosal immunity pathways influences the upper airway microbiome

Catherine Igartua, Emily R Davenport, Yoav Gilad, Dan L Nicolae, Jayant Pinto, Carole Ober

The paper identifies genetic variants associated with upper airway microbiome composition, highlighting mucosal immunity genes' role in shaping microbial communities.

bioRxiv · Jul 5, 2016Genetics

PrediXcan: Trait Mapping Using Human Transcriptome Regulation

Eric R Gamazon, Heather E Wheeler, Kaanan Shah, Sahar V Mozaffari, Keston Aquino-Michaels, Robert J Carroll, Anne E Eyler, Joshua C Denny, Dan L Nicolae, Nancy J Cox, Hae Kyung Im, GTEx Consortium

PrediXcan maps traits to genes by imputing gene expression from GWAS data using reference transcriptomes, identifying disease-associated genes and their mechanisms.

bioRxiv · Jun 17, 2015Genomics