Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse
Marina Wakid, Daniel Almeida, Ryan Denniston, Anjali Chawla, Zahia Aouabed, Maria Antonietta Davoli, Kristin Ellerbeck, Reza Rahimian, Volodymyr Yerko, Elena Leonova-Erko, Gustavo Turecki, Naguib Mechawar
This study identifies widespread gene expression changes in the neurovascular unit of female depressed suicides with childhood abuse histories, highlighting key regulators like KLF2 and KLF4.
Molecular Psychiatry · Oct 30, 2025Peer-reviewedNeuroscience