A mast cell receptor is associated with fibrosis and itch in systemic sclerosis
Ruchita Kothari, Daniel Capuzzi, Collin B. Kilgore, Hyun Jong Oh, Saloni Patel, Anjana Srikumar, Gwen Leatherman, Ami A. Shah, Jun Kang, Xinzhong P Dong
This study identifies Mrgprb2 as a mast cell receptor involved in fibrosis and itch in systemic sclerosis using a mouse model and human tissue analysis.
bioRxiv · Oct 10, 2026 · PreprintImmunology