Author

Daniel Epstein

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

Aharon G. FreudiD· 3 shared Brittney KnottiD· 3 shared Emma D. WrightiD· 3 shared Holly Elizabeth RichteriD· 3 shared Markayla Bell· 3 shared Morgan E. GreeneiD· 3 shared Paige M. PorrettiD· 3 shared Rebecca AsiimweiD· 3 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Aharon G. FreudORCID

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Author profile →

4 papers

Recent·Most cited

Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

Rebecca Asiimwe, Brittney Knott, Morgan E. Greene, Emma Wright, Markayla Bell, Daniel Epstein, Stefani D. Yates, Michael V. Gonzalez, Samantha Fry, Emily A. Boydston, Stephanie Clevenger, Jayme E. Locke, Brian E. Brocato, Constantine M. Burgan, Richard O. Burney, , Paige M. Porrett

The paper identifies NFAT inhibition as a cause of reduced uterine natural killer (uNK) cells and pregnancy complications in humans through analysis of uterus transplant recipients.

Science Translational Medicine · Mar 11, 2026Peer-reviewedImmunology

A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans

Morgan E. Greene, Rebecca Asiimwe, Emma D. Wright, Markayla Bell, Daniel Epstein, Brittney Knott, Samantha Fry, Stephanie Clevenger, Holly Elizabeth Richter, Aharon G. Freud, Shawn C. Little, Paige M. Porrett

This study identifies a developmental program in human uterine NK cells that links tissue residency with divergent effector functions through TGF-β responsive gene regulation.

bioRxiv · Jul 5, 2025 · PreprintImmunology

Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development

Morgan E. Greene, Rebecca Asiimwe, Emma Wright, Markayla Bell, Daniel Epstein, Stefani D. Yates, Brittney Knott, Samantha Fry, Stephanie Clevenger, Jayme E. Locke, Shawn C. Little, Holly Elizabeth Richter, Aharon G. Freud, Paige M. Porrett

This study identifies sequential transcriptional programs of tissue residency driving human uterine NK cell development through single-cell analyses.

bioRxiv · Feb 29, 2024 · PreprintImmunology

Characterization and Preclinical Treatment of Rotational Force-Induced Brain Injury

Alan Umfress, Ayanabha Chakraborti, Suma Priya Sudarsana Devi, Raegan Adams, Daniel Epstein, Adriana V. F. Massicano, Anna G. Sorace, Sarbjit Singh, M. Iqbal Hossian, Shaida A. Andrabi, David K. Crossman, Nilesh Kumar, M. Shahid Mukhtar, Claire M. Simpson, Kathryn Abell, , James A. Bibb

This study develops a rodent model of rotational head trauma, identifies Cdk5 as a key mediator, and shows its inhibition reduces cognitive and pathological effects.

bioRxiv · Jul 20, 2022 · PreprintNeuroscience