Nilesh Kumar

nf_xpatial provides a standardized Nextflow pipeline for preprocessing and clustering Xenium spatial transcriptomics data, enabling reproducible analysis and parameter comparison.

This study uses single-cell RNA sequencing to reveal molecular heterogeneity in quiescent melanocyte stem cells and identifies novel subpopulations with distinct immune privilege and differentiation potential.

This study uses single-nucleus multiomics to uncover drought-driven gene regulatory mechanisms in Arabidopsis, identifying cell type-specific markers and regulatory networks.

This study identifies expanded NKT and NK cells with elevated CD2 in HS lesions and shows CD2 blockade reduces inflammation and fibrosis.

This study develops a rodent model of rotational head trauma, identifies Cdk5 as a key mediator, and shows its inhibition reduces cognitive and pathological effects.

The paper constructs a human-SARS-CoV-2 interactome using network biology and multiomics data to identify key targets and regulatory circuits involved in SARS-CoV-2 pathogenesis.