Author

Daniel Kieffer

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Ashwani Kumar· 1 shared Chao XingiD· 1 shared Chao XingiD· 1 shared Cynthia B. Trygg· 1 shared Erik Allen LykkeniD· 1 shared Harrison HiggsiD· 1 shared Irvin T. GarzaiD· 1 shared Jeanne M. Fisher‐Perkins· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Ashwani Kumar

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1 paper

Recent·Most cited

A minimally modified AAV9 variant (AAV9fyhr) for enhanced CNS gene delivery by intra-CSF administration.

Irvin T. Garza, Vijayashree Ramesh, Yuhui Hu, Matthew Rioux, Mehmet Takar, Harrison Higgs, Erik Allen Lykken, Rachel Adams, Peter Kunach, Daniel Kieffer, Cynthia B. Trygg, Jeanne M. Fisher‐Perkins, Ashwani Kumar, Łukasz A. Joachimiak, Rachel M. Bailey, , Steven James Gray

This paper describes a novel AAV9 variant, AAV9fyhr, that improves CNS gene delivery while minimizing peripheral tissue tropism through targeted amino acid modifications.

bioRxiv · Oct 9, 2026 · PreprintBioengineering