Author

Daniel Lee

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A PaascheiD· 1 shared Agata L. PatriotisiD· 1 shared Alec MerodioiD· 1 shared Alessandra MorettiiD· 1 shared Alicia LundbyiD· 1 shared Alireza Khademi· 1 shared Alison Schroer Vander RoestiD· 1 shared Amy E. KeatingiD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMolecular Biology

A PaascheORCID

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Author profile →

5 papers

Recent·Most cited

Biomechanical stress in the retinal pigment epithelium surrounding laser scars in humans

Yse Borella, Celine Chamette, Jean-Francois Girmens, Cedric Duliere, Florence Rossant, Kiyoko Gocho, Daniel Lee, Ethan A Rossi, Jose-Alain Sahel, Luis Almeida, Marie Darche, Michel Paques

The paper investigates how biomechanical stress in the retinal pigment epithelium (RPE) contributes to the enlargement of laser scars over time using imaging and histological analysis.

bioRxiv · Nov 2, 2026 · PreprintPathology

Beta-Adrenergic Stimulation and MYH7 G256E Mutant Gene Dosage Drive Hypertrophic Cardiomyopathy Phenotype Penetrance

Paul V. Heinrich, Raina M. Jung, Jonathan Samuel Achter, Vincent X. Nguyen, Carissa Lee, Carolin Sailer, Henna Domian, Alison Schroer Vander Roest, Fabian Patrik Suchy, James W.S. Jahng, Ana Kojic, Daniel Lee, A Paasche, Brock Roberts, Hiromitsu Nakauchi, , Sean M. Wu

This study investigates factors influencing HCM phenotype penetrance by comparing MYH7 mutations in isogenic hiPSC-CMs and shows that beta-adrenergic stimulation and gene dosage affect disease expression.

bioRxiv · Jun 6, 2026 · PreprintMolecular Biology

Multiomic screening platform uncovers the impact of histone mutations on chromatin and cell fate

Ziyang Ye, Alireza Khademi, Renée Louane Barbosa, Foster Birnbaum, Margaret R. Brown, Colin E Fowler, Arianna Arroyo-Ortega, Daniel Lee, Lijuan Feng, Leah A. Gates, Agata L. Patriotis, Amy E. Keating, Francisco J. Sánchez Rivera, Yadira M. Soto‐Feliciano

This study develops CHANCLA, a multiomic platform to screen oncohistones, revealing their impact on chromatin and cell fate through functional and structural analyses.

bioRxiv · Apr 17, 2026 · PreprintCancer Biology

Intercellular communication in the brain via dendritic nanotubular network

Minhyeok Chang, Sarah Krüssel, Laxmi Kumar Parajuli, Juhyun Kim, Daniel Lee, Alec Merodio, Jaeyoung Kwon, Shigeo Okabe, Hyung‐Bae Kwon

This study identifies dendritic nanotubular networks in mammalian brains that facilitate intercellular communication and are implicated in Alzheimer's disease pathology.

bioRxiv · May 20, 2025 · PreprintNeuroscience

How Our Cells Become Our Selves: The Cellular Phylodynamic Biology of Growth and Development

Philip S. Chodrow, Jessica Ann Lasky-Su, Daniel Lee, Tahmid Ahmed, Neil He, Ruben De Man, Ankur Tiwari, William P. Mannherz, Luca Citi, Daniel DiCorpo, James Selib Michaelson

The paper introduces two new growth processes, UNI-GROWTH and ALLO-GROWTH, and their mathematical equations to model cellular development across species.

bioRxiv · Sep 22, 2021 · PreprintDevelopmental Biology