Evolutionary trade-offs between growth and reproduction under obesogenic conditions: sex-biased skeletal and gonadal maturation in mice
Clarissa R. Coveney, Amar Sarkar, Neil G.O. Ibata, David E. Maridas, Devandar Kaushik, Alanah McKeever, Jenna Shoman, Seiji Aoki, Talia Kahan, Cary R. Allen‐Blevins, Danalaxshmi Shanen Ganapathee, Alexander S. Okamoto, Gayani Senevirathne, Emily M. Venable, Grace Rubin, , Terence Dante Capellini
This study shows that high-fat diets during adolescence shift energy allocation in mice toward reproduction, affecting skeletal and metabolic health differently in males and females.
bioRxiv · Jul 21, 2026 · PreprintEvolutionary Biology