GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
Janina Müller, Emre Sofyalı, Luisa E. Schwarzmüller, Yael Aylon, Eviatar Weizman, Lisa Schlicker, Katherine Kelly, Simone Borgoni, Simin Oz, Cole Stocker, Sara Burmester, Angelika Wörner, Sabine Karolus, Birgitta E. Michels, Daniela Heiss, , Stefan Wiemann
This study identifies GLYATL1 as a mediator of endocrine resistance in luminal breast cancer by promoting metabolic and epigenetic changes that counteract estrogen deprivation.
Clinical Epigenetics · Apr 29, 2026Peer-reviewedCancer Biology