Microglia drive pockets of neuroinflammation in middle age
Eric N. Moca, Daniela Lecca, Keenan T. Hope, Fanny Etienne, Ari W. Schaler, Katherine Espinoza, Megan S. Chappell, Daniel T. Gray, David Tweedie, Shanaya Sidhu, Lindsay Masukawa, Hannah Sitoy, Rose Mathew, Daniel R. Saban, Nigel H. Greig, Lindsay M. De Biase
The paper shows that microglia in specific brain regions exhibit premature aging-related inflammation in middle age, which may affect nearby neurons.
Journal of Neuroscience · Apr 8, 2022Peer-reviewedNeuroscience