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Bioinformatics· 1

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

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Chunyi Wang· 1 shared Jichuan Yu· 1 shared Jinhong Lu· 1 shared M KellisiD· 1 shared Meizhen Lin· 1 shared Qi Xie· 1 shared Qing Yang· 1 shared Weixiang WangiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Chunyi Wang

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Recent·Most cited

Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution

Chunyi Wang, Wenxuan Fan, Weixiang Wang, Yonghe Xia, Jinhong Lu, Xiaoyu Ma, Jichuan Yu, Yunchao Zheng, Qing Yang, Meizhen Lin, X F Yu, Xushen Xiong, M Kellis, Qi Xie, Yanmei Dou, Data Group

The paper develops BayesMonSTR to detect mosaic STR mutations at single-cell resolution and finds increased STR indels in aging cells, particularly in prefrontal cortex neurons.

bioRxiv · Apr 5, 2026 · PreprintBioinformatics