Unifying N- and O-glycopeptide dissociation methods with expedient electron transfer dissociation
Haley M. Schramm, Tim S. Veth, Joshua D. Hinkle, JingJing Huang, David Bergen, Rafael Donadelli Melani, Graeme C. McAlister, Christopher Mullen, Nicholas McIlvain Riley
This paper improves ETD-based fragmentation for glycopeptide analysis by optimizing ion handling and scan parameters, making it faster and more efficient for both N- and O-glycopeptides.
bioRxiv · Oct 14, 2026 · PreprintSystems Biology