Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis
Amy Eapen, Sreeja Parameswaran, Carmy R. Forney, Lee Edsall, Daniel Miller, Omer A. Donmez, Katelyn Dunn, Xiaoming Lu, Marissa Granitto, Hope Rowden, Adam Z. Magier, Mario Andres Pujato, Xiaoting Chen, Kenneth M. Kaufman, David I Bernstein, , Leah Claire Kottyan
This study identifies epigenetic and transcriptional dysregulation in CD4+ T cells of atopic dermatitis patients, linking genetic risk variants to altered chromatin accessibility and NFKB1 binding.
Journal of Allergy and Clinical Immunology · Feb 1, 2022Peer-reviewedGenomics