Purifying circular RNA by ultrafiltration
Karen Guillen-Cuevas, Xiaoming Lu, Marc R. Birtwistle, Scott M. Husson
This study demonstrates that ultrafiltration can purify circRNA with 86% purity and 50% yield, outperforming SE-HPLC.
Author
Cincinnati Children's Hospital Medical CenterORCID 0000-0002-0830-2826Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Karen Guillen-Cuevas, Xiaoming Lu, Marc R. Birtwistle, Scott M. Husson
This study demonstrates that ultrafiltration can purify circRNA with 86% purity and 50% yield, outperforming SE-HPLC.
Amy Eapen, Sreeja Parameswaran, Carmy R. Forney…·Leah Claire Kottyan
This study identifies epigenetic and transcriptional dysregulation in CD4+ T cells of atopic dermatitis patients, linking genetic risk variants to altered chromatin accessibility and NFKB1 binding.
Xiaoming Lu, Xiaoting Chen, Carmy R. Forney…·Leah Claire Kottyan
The paper identifies 482 SLE risk variants with enhancer activity and characterizes allelic regulatory mechanisms at 27 risk loci using MPRA.
Guojun Hou, Isaac T. W. Harley, Xiaoming Lu…·Nan Shen
The paper identifies a non-coding genetic variant associated with SLE that regulates miR-146a expression through a cell-type specific enhancer.
Daniel E. Miller, Carmy R. Forney, Mark Rochman…·Leah Claire Kottyan
The paper investigates how genetic, inflammatory, and epithelial cell differentiation factors regulate CAPN14 expression in eosinophilic esophagitis.