Author

Deepak Pathak

Houston Methodist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Lina Sun· 2 shared Rashmi Basavaraj· 2 shared Yi‐Lan WengiD· 2 shared Aitor Rodríguez‐CasanovaiD· 1 shared Alexandre HarléiD· 1 shared Alexis RapiniD· 1 shared Anes Hadjadj AouliD· 1 shared Ángel Díaz‐LagaresiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Lina Sun

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of m6A unmasks a senescence-associated inflammatory program in human microglia

Deepak Pathak, Rashmi Basavaraj, Lina Sun, Yi‐Lan Weng

This study shows that reducing m6A in human microglia induces a senescence-like inflammatory state through specific RNA changes and nuclear remodeling.

bioRxiv · Jul 8, 2026 · PreprintNeuroscience

Analytical Validation of a Pan-Cancer NGS Assay for In-House Liquid Biopsy Testing: An International Multicenter Study

Gaëlle Lescuyer, Alexandre Harlé, Hari Shankar Kumar, Pantelis Constantoulakis, Nicole Pfarr, Ellen Heitzer, Clémence Michon, Gianluca Russo, Ernst‐Jan M. Speel, Marie Piecyk, Marie Husson, Georgia Christopoulou, Eva-Maria Mayr, Mai-Lan Koppermann, Christophe Passot, , Lea Francoise Payen

This study validates a pan-cancer NGS assay for liquid biopsy testing across multiple centers, showing high sensitivity and specificity for detecting genomic alterations in cfDNA.

Journal of Molecular Diagnostics · Sep 25, 2025Peer-reviewedGenetic & Genomic Medicine

Deficiency of m6A RNA methylation promotes ZBP1-mediated cell death

Shuang Li, Xiangyu Deng, Deepak Pathak, Rashmi Basavaraj, Lina Sun, Yating Cheng, Jianrong Li, Marissa Burke, Gavin Wayne Britz, Chao Cheng, Yang Gao, Yi‐Lan Weng

The paper shows that m6A deficiency leads to 7SK RNA activation of the RIG-I/MAVS axis and ZBP1-mediated necroptotic cell death through IFN and rG4 synergies.

bioRxiv · Jun 29, 2024 · PreprintMolecular Biology