A curated human lactylome and protein language model framework enable accurate prediction and reveal local determinants of lysine lactylation
Zhengda Li, Youcheng Huang, Guangyao Shan, Di Zuo, Junhe Zhang, Yuqiang Du, Dejun Zeng, Xiliang Wang, Liang Chen, Hong Fan, Guangyu Yao
The paper introduces CLEAR-Lactyl, a curated dataset of human lysine lactylation sites, and AttentionKla, a deep learning model that accurately predicts lactylation sites and reveals sequence determinants.
bioRxiv · Jul 31, 2026 · PreprintBioinformatics