AmpliconSuite: an end-to-end workflow for analyzing focal amplifications in cancer genomes
Jens Luebeck, Edwin Huang, Forrest Kim, Ted Liefeld, Bhargavi Dameracharla, Rohil Ahuja, Daniel Schreyer, Gino Prasad, Michał Adamaszek, Rishaan Kenkre, Tushar Agashe, Devika Torvi, Thorin T. Tabor, Mădălina Giurgiu, So Yeon Kim, , Vineet Bafna
AmpliconSuite identifies focal amplifications in cancer genomes, showing ecDNA has higher copy numbers and stronger oncogene enrichment compared to other amplification types.
bioRxiv · May 6, 2024 · PreprintBioinformatics