Author

Devin A. Bradburn

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mardo KõivomägiiD· 2 shared Gretchen Heidebrink· 1 shared Haribabu ArthanariiD· 1 shared Hyunbum JangiD· 1 shared Joana ReisiD· 1 shared Liz KoganiD· 1 shared Martha CyertiD· 1 shared Michelle Leiser· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Mardo KõivomägiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Uncovering cancer dependencies in peptide-interacting protein pockets

Mihkel Örd, Liz Kogan, Devin A. Bradburn, Michelle Leiser, Mardo Kõivomägi, Norman E. Davey, Pau Creixell

The paper screens peptide-binding pockets across cancer cell lines to identify therapeutic vulnerabilities and dependencies, finding that peptide inhibition can reveal hidden dependencies and enhance drug efficacy.

bioRxiv · Mar 15, 2026 · PreprintCancer Biology

A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin

Devin A. Bradburn, Joana Reis, Rosamaria Y. Moreno, Shariq Qayyum, Thibault Viennet, Haribabu Arthanari, Martha Cyert

The paper identifies a novel composite motif in CLMB that enables multimeric dephosphorylation by calcineurin, influencing its membrane localization and signaling.

Nature Communications · Nov 12, 2025Peer-reviewedBiochemistry

Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance

Wengang Zhang, Devin A. Bradburn, Gretchen Heidebrink, Yonglan Liu, Hyunbum Jang, Ruth Nussinov, Mardo Kõivomägi

This study identifies distinct allosteric networks in CDK4 and CDK6 that explain their differential kinase activity, inhibitor binding, and roles in cell cycle regulation and drug resistance.

Journal of Molecular Biology · Apr 2, 2025Peer-reviewedMolecular Biology