Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers
Fereshteh Sadeqi, Dexin Dong, Kai Steffen Stroh, Marian Vache, Jutta Metz, Dietmar Riedel, Andreas Janshoff, Herre Jelger Risselada, Caroline Kolenda, Michael Meinecke
The paper shows Ups1 preferentially binds to positively curved membranes, facilitating phosphatidic acid transfer between mitochondrial membranes.
bioRxiv · Apr 3, 2025 · PreprintBiochemistry