Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation
Gaurav Agarwal, Mateusz Antoszewski, Xuejun Xie, Yash Pershad, Uma P. Arora, Chi-Lam Poon, Peng Lyu, Andrew J. Lee, C. Guo, Tianyi Ye, Laila Barakat Norford, Anna‐Lena Neehus, Lucrezia della Volpe, Lara Wahlster, Diyanath Ranasinghe, , Vijay G. Sankaran
The paper identifies a genetic variant that protects against clonal hematopoiesis by regulating RNA-binding protein MSI2 in hematopoietic stem cells.
Science · Jan 1, 2026Peer-reviewedGenetics