A CLN6-CRMP2-KLC4 complex regulates anterograde ER-derived vesicle trafficking in cortical neurites
SY Koh, JT Cain, Helen Magee, Katherine A. White, Mitchell J. Rechtzigel, Brandon L. Meyerink, Hannah G. Leppert, DJ Timm, JP Morgan, TB Johnson, Bryon D. Grove, Rajesh Khanna, Kenneth Hensley, Jon J. Brudvig, Jill M. Weimer
This study identifies a novel CCK complex involving CLN6, CRMP2, and KLC4 that regulates ER-derived vesicle transport in axons, with implications for neurodegenerative disease therapy.
bioRxiv · Sep 16, 2021 · PreprintNeuroscience