A Humanized Monoclonal Antibody against the Enzymatic Subunit of Ricin Toxin Rescues Rhesus macaques from the Lethality of Aerosolized Ricin
Chad J. Roy, Dylan J. Ehrbar, Natasha Bohorova, Ognian Bohorov, Do Kim, Michael Pauly, Kevin Whaley, Yinghui Rong, Fernando J Torres-Velez, Ellen S Vitetta, Peter J. Didier, Lara Doyle-Meyers, Larry Zeitlin, Nicholas J. Mantis
This study shows that huPB10, a humanized monoclonal antibody, can rescue rhesus macaques from lethal ricin exposure when administered within four hours of aerosolized ricin exposure.
bioRxiv · Sep 6, 2018 · PreprintImmunology