Author

Douglas Faget

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

David DeNardo· 1 shared Edward CamposiD· 1 shared Ganesh Raut· 1 shared Jingqin LuoiD· 1 shared Radhika MishraiD· 1 shared Renata Ferreira· 1 shared Sheila A. StewartiD· 1 shared Xianmin LuoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

David DeNardo

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1 paper

Recent·Most cited

Targeting MK2-Driven Stromal Senescence Sensitizes Breast Cancer Bone Metastasis to Immunotherapy

Renata Ferreira, Douglas Faget, Radhika Mishra, Ganesh Raut, Edward Campos, Xianmin Luo, Yu Tao, Jingqin Luo, David DeNardo, Sheila A. Stewart

This study identifies senescent cancer-associated fibroblasts (senCAFs) driven by MK2 that promote immunosuppression in bone metastases and shows that combining MK2 inhibition with OX40 agonists enhances immunotherapy efficacy.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology