Author

Douglas Galasko

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Afina Willemina LemstraiD· 1 shared Alberto LleóiD· 1 shared Andreas KelleriD· 1 shared Andrew John LeesiD· 1 shared Andrew SingletoniD· 1 shared Angelo D' Alessandro· 1 shared Anne BraaeiD· 1 shared Ayk Petrosyan· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperNeuroscience

Afina Willemina LemstraORCID

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3 papers

Recent·Most cited

Nuclear acetyl-CoA accumulation drives reversible RBP hyperacetylation and transcriptome-wide splicing shifts in age-equivalent Alzheimer's disease neurons

Larissa Traxler, Oliver Borgogno, Kylie Champion, Joseph R. Herdy, Monika Dzieciątkowska, Julie A. Reisz, Ayk Petrosyan, Cat Siler, Colin C. Anderson, Elisa Gorostieta-Salas, Raffaella Lucciola, Douglas Galasko, Fred H. Gage, Angelo D' Alessandro, Jérôme Mertens

This study shows that nuclear acetyl-CoA accumulation in Alzheimer's disease neurons causes RBP hyperacetylation and splicing shifts, which can be reversed by inhibiting ACLY.

bioRxiv · Oct 1, 2026 · PreprintNeuroscience

Deep sncRNA-seq of the PPMI cohort to study Parkinson's disease progression

Fabian Kern, Tobias Fehlmann, Ivo Violich, Eric B. Alsop, Elizabeth D. Hutchins, Mustafa Kahraman, Nadja Liddy Grammes, Pedro Guimarães, Christina Backes, Kathleen L. Poston, Bradford H. Casey, Rudi Balling, Lars Geffers, Rejko Krüger, Douglas Galasko, , Andreas Keller

The paper analyzes sncRNA-seq data from the PPMI cohort to identify miRNAs associated with Parkinson's disease progression and systemic inflammation.

Nature Aging · Mar 15, 2021Peer-reviewedNeuroscience

Heritability and genetic variance of dementia with Lewy bodies

Rita João Guerreiro, Valentina Escott‐Price, Dena G. Hernandez, Célia Kun‐Rodrigues, Owen A. Ross, Tatiana Orme, João Luís Neto, Susana Carmona, Nadia Dehghani, John D. Eicher, Claire E. Shepherd, Laura Parkkinen, Lee Darwent, Michael G. Heckman, Sonja W. Scholz, , José Brás

This study estimates the heritability of dementia with Lewy bodies (DLB) and finds it to be higher than previous estimates, with low variance explained by polygenic risk scores from Parkinson's or Alzheimer's disease.

Neurobiology of Disease · Apr 3, 2019Peer-reviewedNeuroscience