BiochemistrybioRxivPreprint
A DNA damage-induced phosphorylation circuit enhances Mec1ATR-Ddc2ATRIP recruitment to Replication Protein A.
L. A. Yates, E. A. Tannous, R. M. Morgan…·X. Zhang
This paper shows that phosphorylation enhances Mec1-Ddc2 recruitment to RPA-ssDNA, facilitating DNA damage checkpoint signaling in yeast.
DOI 10.1101/2022.12.23.521831