Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours
J. Kendler, F. Woels, S. Thapliyal, E. Arcalis, H. Gabriel, S. Kubitschek, D. Malzl, M. R. Strobl, D. Palmberger, T. Luber, C. Unverzagt, K. Paschinger, D. A. Glauser, I. B. H. Wilson, S. Yan
This study identifies AMAN-3 as a Golgi α-mannosidase essential for tri-fucosylation of nematode N-glycans, which affects growth and behavior in C. elegans.
bioRxiv · Jul 18, 2024Biochemistry