An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries
B. M. Petersen, M. Kirby, K. Chrispens, O. Irvin, I. Strawn, C. Haas, A. Walker, Z. T. Baumer, S. Ulmer, E. Ayala, O. Irvin, E. R. Rhodes, J. Guthmiller, P. J. Steiner, T. A. Whitehead
The paper introduces MAGMA-seq, a technology for quantitative analysis of antibody sequence-function relationships, demonstrating its application in mapping antibody development pathways and identifying binding determinants.
Nature Communications · May 10, 2024Peer-reviewedBiochemistry