Spatial omics imaging of fresh-frozen tissue and routine FFPE histopathology on a single cancer needle core biopsy: freezing device and multimodal workflow
M. F. Rittel, S. Schmidt, C.-A. Weis, E. Birgin, B. van Marwick, M. Raedle, S. Diehl, N. Rahbari, A. Marx, C. Hopf
The paper develops a device and workflow for multimodal spatial omics analysis of fresh-frozen and FFPE-processed needle biopsy cores to enable simultaneous molecular and histopathological analysis of cancer tissue.
bioRxiv · Feb 11, 2023Cancer Biology