Loss of GdpP function in Staphylococcus aureus leads to β-lactam tolerance and enhanced evolution of β-lactam resistance
R. Poon, L. Basuino, N. Satishkumar, A. Chatterjee, N. Mukkayyan, E. Buggeln, L. Huang, V. Nair, M. A. Argudin, S. K. Datta, H. F. Chambers, S. S. Chatterjee
This study shows that loss of GdpP function in Staphylococcus aureus increases β-lactam tolerance and facilitates the evolution of β-lactam resistance.
bioRxiv · Jul 2, 2021Microbiology