Genetic and epigenetic driven variation in regulatory regions activitycontribute to adaptation and evolution under endocrine treatment
N. Slaven, R. Lopes, E. Canale, D. Ivanoiu, C. Pacini, I. A. Monteiro Barbosa, M. Bleu, S. Bravaccini, S. Ravaioli, M. V. Dieci, G. Pruneri, G. Galli, I. Barozzi, L. Magnani
This study identifies non-coding DNA alterations in hormone-dependent breast cancer that contribute to endocrine therapy resistance and disease progression.
bioRxiv · Feb 15, 2022 · PreprintCancer Biology