An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
M. Neidlin, E. Chantzi, G. Macheras, M. Gustafsson, L. G. Alexopoulos
The paper establishes an ex vivo cartilage model to identify protein patterns distinguishing healthy from degraded cartilage, finding that MMP9 and IFNG pairs can accurately classify samples.
bioRxiv · Feb 5, 2019Bioengineering