Author

M. Gustafsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Backlund· 1 shared A. Farnert· 1 shared A. Gorgens· 1 shared A. Julia· 1 shared A. L. Gallina· 1 shared A. S. Caravaca· 1 shared B. Bostancioglu· 1 shared C. I. E. Smith· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioengineering

A. Backlund

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

scDrugPrio: A framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases

S. Schaefer, M. Smelik, O. Sysoev, Y. Zhao, D. Eklund, S. Lilja, M. Gustafsson, H. Heyn, A. Julia, I. A. Kovacs, J. Loscalzo, S. Marsal, H. Zhang, X. Li, D. Gawel, , M. Benson

scDrugPrio uses single-cell RNA sequencing to prioritize drugs for immune-mediated inflammatory diseases, showing personalized drug response variations across patients.

bioRxiv · Nov 8, 2023Immunology

Identification and Characterization of Human Activation-Induced ChAT+CD4+ T Cells

L. Tarnawski, A. L. Gallina, E. J. Kort, V. S. Shavva, Z. Zhuge, D. Martinez Enguita, M. Weiland, A. S. Caravaca, S. Schmidt, F.-H. Wang, A. Farnert, E. Weitzberg, M. Gustafsson, M. Eberhardson, H. Hult, , P. S. Olofsson

The paper identifies and characterizes human ChAT+CD4+ T cells, showing their induction by activation and association with vasorelaxation and improved survival in critically ill patients.

bioRxiv · Apr 27, 2021 · PreprintImmunology

Progesterone specifically dampens disease-associated TH1- and TH17-related immune responses during T cell activation in vitro

S. Hellberg, J. Raffetseder, O. Rundquist, R. Magnusson, G. Papapavlou, M. C. Jenmalm, J. Ernerudh, M. Gustafsson

This study shows progesterone dampens TH1 and TH17 immune responses in T cells by altering gene and protein expression, with implications for pregnancy-related autoimmune disease modulation.

bioRxiv · Nov 5, 2020 · PreprintImmunology

Engineering of extracellular vesicles for display of protein biotherapeutics

D. Gupta, O. P. B. Wiklander, A. Gorgens, M. Conceicao, G. Corso, X. Liang, Y. Seow, S. Balsu, U. Felldin, B. Bostancioglu, Y. X. F. Lee, J. Hean, I. Mager, T. C. Roberts, M. Gustafsson, , S. E. Andaloussi

This paper develops a platform to display multiple protein therapeutics on extracellular vesicles, showing improved efficacy in inflammatory disease models compared to existing biologics.

bioRxiv · Jun 14, 2020Bioengineering

An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns

M. Neidlin, E. Chantzi, G. Macheras, M. Gustafsson, L. G. Alexopoulos

The paper establishes an ex vivo cartilage model to identify protein patterns distinguishing healthy from degraded cartilage, finding that MMP9 and IFNG pairs can accurately classify samples.

bioRxiv · Feb 5, 2019Bioengineering