The oncogenic fusion protein EWS-FLI1 promotes premature ageing of biomolecular condensates by catalyzing fibril formation.
E. E. Selig, A. K. Romero-Moreno, S. Akula, X. Xu, D. S. Libich
This study shows EWS-FLI1 promotes premature ageing of biomolecular condensates by catalyzing fibril formation through interactions with EWSLCD.
bioRxiv · Jun 4, 2022 · PreprintBiophysics