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E. E. Wade

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Evolutionary Biology· 1

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Assay:DNA methylation· 1 Organism:Drosophila· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

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C. Kyriazis· 1 shared K. E. Lohmueller· 1 shared M. I. A. Cavassim· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperEvolutionary Biology

C. Kyriazis

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1 paper

Recent·Most cited

Quantifying the fraction of new mutations that are recessive lethal

E. E. Wade, C. Kyriazis, M. I. A. Cavassim, K. E. Lohmueller

The paper quantifies the fraction of new mutations that are recessive lethal using simulations and genomic data, finding that less than 1% of nonsynonymous mutations are recessive lethal in humans and Drosophila.

bioRxiv · Apr 22, 2022Evolutionary Biology