Antibody-drug conjugates to treat bacterial biofilms
A. Tvilum, M. Illemann Johansen, L. Glud, D. M. Ivarsen, A. B. Khamas, S. Carmali, S. Satish Mhatre, A. B. Sogaard, E. Faddy, L. de Vor, S. Rooijakkers, L. Ostergaard, N. J. Pedersen, R. L. Meyer, A. N. Zelikin
This paper develops antibody-drug conjugates that kill bacteria in biofilms and in vivo, showing superior antimicrobial effects compared to standard antibiotics.
bioRxiv · Jan 16, 2023 · PreprintMicrobiology