BiochemistrybioRxivPreprint
Temporal Effects of Galactose and Manganese Supplementation on Monoclonal Antibody N-Linked Glycosylation in Fed-Batch and Perfusion Bioreactor Operation
A. Gyorgypal, E. Fratz-Berilla, C. Kohnhorst…·S. P. S. Chundawat
This study examines how galactose and manganese supplementation affects Trastuzumab N-glycosylation over time in fed-batch and perfusion bioreactors, showing temporal changes in glycoform composition.
DOI 10.1101/2023.04.15.535602