Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition
P. Skowronek, F. Krohs, M. Lubeck, G. Wallmann, E. Itang, P. Koval, M. Wahle, M. Thielert, F. Meier, S. Willems, O. Raether, M. Mann
This paper introduces synchro-PASEF, a method that improves fragment ion extraction and interference removal in DIA proteomics by synchronizing ion mobility and mass dimensions.
bioRxiv · Nov 1, 2022Biochemistry