Author

M. Thielert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 5 Organism:human· 4 Approach:deep learning· 3 Research Focus:protein folding & dynamics· 3 Research Focus:benchmarking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

M. Mann· 5 shared P. Skowronek· 3 shared A.-D. Brunner· 2 shared F. Meier· 2 shared M. Wahle· 2 shared S. Willems· 2 shared A. Erturk· 1 shared A. Metousis· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersBiochemistry

M. Mann

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Author profile →

5 papers

Recent·Most cited

The potential of plasma HLA peptides beyond neoepitopes

M. Wahle, M. Thielert, M. Zwiebel, P. Skowronek, W.-F. Zeng, M. Mann

The paper develops a sensitive method to analyze HLA peptides in plasma, revealing stable and tissue-representative immunopeptidomes with potential for biomarker discovery.

bioRxiv · Sep 5, 2023 · PreprintBiochemistry

A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics

T. M. Nordmann, L. Schweizer, A. Metousis, M. Thielert, E. Rodriguez, L. M. Rahbek-Gjerdrum, P.-C. Stadler, M. Bzorek, A. Mund, F. A. Rosenberger, M. Mann

This paper introduces a workflow for using membrane glass slides in histology and spatial proteomics, improving compatibility with automated staining and preserving antigen retrieval.

bioRxiv · Feb 20, 2023Pathology

Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition

P. Skowronek, F. Krohs, M. Lubeck, G. Wallmann, E. Itang, P. Koval, M. Wahle, M. Thielert, F. Meier, S. Willems, O. Raether, M. Mann

This paper introduces synchro-PASEF, a method that improves fragment ion extraction and interference removal in DIA proteomics by synchronizing ion mobility and mass dimensions.

bioRxiv · Nov 1, 2022Biochemistry

Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF

P. Skowronek, M. Thielert, E. Voytik, M. C. Tanzer, F. M. Hansen, S. Willems, O. Karayel, A.-D. Brunner, F. Meier, M. Mann

This paper introduces an optimized dia-PASEF method with variable isolation windows to enhance proteome and phosphoproteome coverage in mass spectrometry.

bioRxiv · May 31, 2022Biochemistry

Proteomics of spatially identified tissues in whole organs

H. S. Bhatia, A.-D. Brunner, Z. Rong, H. Mai, M. Thielert, R. Al-Maskari, J. C. Paetzold, F. Kofler, M. I. Todorov, M. Ali, M. Molbay, Z. I. Kolabas, D. Kaltenecker, S. Mueller, S. F. Lichtenthaler, , A. Erturk

This paper introduces DISCO-MS, a method for spatial proteomics of whole organs, and shows it provides proteomics data comparable to fresh tissues in rodent and human samples.

bioRxiv · Nov 2, 2021 · PreprintBioengineering