Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas
M. F. Orth, V. L. Buecklein, E. Kampmann, M. Subklewe, E. Noessner, F. Cidre-Aranaz, L. Romero-Perez, F. S. Wehweck, L. Lindner, R. Issels, T. Kirchner, A. Altendorf-Hofmann, T. G. P. Grunewald, T. Knoesel
This study examines PD-L1 and PD-1 expression in soft tissue sarcomas and finds associations with TILs and poor clinical outcomes, supporting immune checkpoint inhibition in PD-L1-positive cases.
bioRxiv · Mar 8, 2019 · PreprintCancer Biology