E. Kingma

Global genetic rewiring during compensatory evolution in the yeast polarity network

This study shows that compensatory mutations in yeast rewiring gene fitness across cellular processes, not just individual genes, highlighting the role of functional overlap and network interconnectedness.

Saturated Transposon Analysis in Yeast as a One-step Method to Quantify the Fitness Effects of Gene Disruptions on a Genome-Wide Scale

The paper introduces a method to quantify gene disruption fitness effects using TIS data in yeast, showing that average read counts per insertion site provide a robust fitness metric.

Pleiotropy allows recovery of phenotypic plasticity in constant environments

This study shows that phenotypic plasticity can recover in both fluctuating and constant environments through pleiotropic interactions, challenging the idea that plasticity only evolves in fluctuating conditions.