Author

E. L. Bruger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 5 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. J. Marx· 3 shared C. M. Waters· 2 shared A. M. Buechlein· 1 shared C. Fuqua· 1 shared C. J. Renshaw· 1 shared D. Crosby· 1 shared D. E. Deatherage· 1 shared D. J. Synder· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

C. J. Marx

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Global transcriptional response of Methylorubrum extorquens to formaldehyde stress expands the role of EfgA and is distinct from antibiotic translational inhibition

J. Bazurto, S. Riazi, S. D'Alton, D. E. Deatherage, E. L. Bruger, J. E. Barrick, C. J. Marx

This study examines how Methylorubrum extorquens responds to formaldehyde stress with and without EfgA, revealing its role in transcriptional regulation and stress response.

bioRxiv · Jan 7, 2021Microbiology

Epistatic interactions shape the interplay between beneficial alleles and gain or loss of pathways in the evolution of novel metabolism

E. L. Bruger, L. M. Chubiz, J. I. Rojas Echenique, C. J. Renshaw, N. V. Espericueta, J. A. Draghi, C. J. Marx

The paper investigates how epistatic interactions affect the fitness of beneficial alleles in different genetic backgrounds, showing that alleles beneficial in one context can be deleterious in others, impacting the evolution of novel metabolic pathways.

bioRxiv · Oct 20, 2020 · PreprintEvolutionary Biology

Formaldehyde-responsive proteins, TtmR and EfgA, reveal a tradeoff between formaldehyde resistance and efficient transition to methylotrophy in Methylorubrum extorquens

J. V. Bazurto, E. L. Bruger, J. A. Lee, L. B. Lambert, C. J. Marx

bioRxiv · Oct 19, 2020Microbiology

Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation

E. L. Bruger, D. J. Synder, V. S. Cooper, C. M. Waters

The paper shows that quorum sensing (QS) in Vibrio harveyi maintains cooperation by preventing defectors from outcompeting cooperators over evolutionary timescales.

bioRxiv · Jun 29, 2020Evolutionary Biology

Reciprocal control of motility and biofilm formation by the PdhS2 two-component sensor kinase of Agrobacterium tumefaciens

J. E. Heindl, D. Crosby, S. Brar, T. Singletary, D. Merenich, J. L. Eagan, A. M. Buechlein, E. L. Bruger, C. M. Waters, C. Fuqua

This paper investigates how the PdhS2 sensor kinase in Agrobacterium tumefaciens regulates biofilm formation and motility through interactions with DivK and CtrA, affecting cdGMP levels and adhesive polysaccharide production.

bioRxiv · Mar 30, 2018Microbiology