Author

E. L. Stone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Adler· 1 shared A. Gras· 1 shared A. Niedecken· 1 shared B. K. Gautam· 1 shared B. Tinsley· 1 shared C. Edgar· 1 shared D. S. Johnson· 1 shared E. Benzie· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. A. Adler

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1 paper

Recent·Most cited

Lack of blocking activity in anti-CTLA-4 antibodies reduces toxicity, but not anti-tumor efficacy

E. L. Stone, K. P. Carter, E. K. Wagner, M. A. Asensio, E. Benzie, Y. Y. Chiang, G. L. Coles, C. Edgar, B. K. Gautam, A. Gras, J. Leong, R. Leong, V. A. Manickam, R. A. Mizrahi, A. Niedecken, , D. S. Johnson

This study shows that anti-CTLA-4 antibodies with reduced checkpoint inhibition have better anti-tumor efficacy and lower toxicity by primarily depleting tumor-infiltrating Tregs via FcR signaling.

bioRxiv · Jul 12, 2021 · PreprintImmunology