Structural basis of organic cation transporter-3 inhibition
B. Khanppnavar, J. Maier, F. Herborg, R. Gradisch, E. Lazzarin, D. Luethi, J.-W. Yang, C. Qi, M. Holy, K. Jaentsch, O. Kudlacek, K. Schicker, T. Werge, U. Gether, T. Stockner, , H. H. Sitte
The paper determines the cryo-EM structure of OCT3 and analyzes genetic variants to understand its function and inhibition.
bioRxiv · Jul 14, 2022Pharmacology & Toxicology