Hypersensitivity of MAIT cells to Leukocidin ED indicates a Staphylococcus aureus immune evasion mechanism targeting the innate effector cell response
C. Boulouis, E. Leeansyah, S. M. Shambat, A. Norrby-Teglund, J. K. Sandberg
This study shows that Staphylococcus aureus toxin LukED selectively kills MAIT cells and CD57+ NK cells, impairing early innate immune responses.
bioRxiv · Jul 15, 2021 · PreprintImmunology