DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A
K. E. Leon, R. Buj, E. Lesko, E. S. Dahl, C.-W. Chen, Y. Imamura Kawasawa, A. V. Kossenkov, R. P. Hobbs, K. M. Aird
This study shows that DOT1L regulates the senescence-associated secretory phenotype (SASP) through epigenetic control of IL1A expression in oncogene-induced senescence.
bioRxiv · Aug 21, 2020Cell Biology