Discovery of a Pseudomonas aeruginosa Type VI secretion system toxin targeting bacterial protein synthesis using a global genomics approach
L. M. Nolan, A. K. Cain, E. Manoli, M. A. Sainz-Polo, G. Dougan, D. A. I. Mavridou, D. Albesa-Jove, J. Parkhill, A. Filloux
The paper uses TraDIS to identify T6SS toxins in Pseudomonas aeruginosa, finding Tse8 targets bacterial protein synthesis by disrupting the transamidosome complex.
bioRxiv · Aug 13, 2019 · PreprintMicrobiology