Enhanced Anticoagulation Activity of Functional RNA Origami
A. Krissanaprasit, C. M. Key, K. Froehlich, S. Pontula, E. Mihalko, D. M. Dupont, E. S. Andersen, J. Kjems, A. C. Brown, T. H. LaBean
This paper develops RNA origami displaying RNA aptamers as anticoagulants, showing enhanced thrombin inhibition and reversible activity with potential for clinical use.
bioRxiv · Sep 29, 2020 · PreprintBioengineering